Research Associate 1

POSITION DURATION:

This is a six-month contract role located in San Carlos with the potential to extend or convert to full-time based on performance and business needs.

POSITION SUMMARY:  

Join Natera’s Oncology Research Use Only (RUO) Histopathology team as a Research Associate. You will independently execute molecular biology experiments, process laboratory specimens, and operate Next-Generation Sequencing (NGS) workflows. Every sample represents a real person, and you will work in a fast-paced, highly regulated environment that balances a deep mission for patient care with strict execution.

PRIMARY RESPONSIBILITIES:

• Process laboratory specimens following standard methods with high attention to detail, maintaining strict protocols to avoid cross-contamination
• Isolate plasma from whole blood manually, and perform tissue dissections for both Fresh and Formalin-Fixed Paraffin-Embedded (FFPE) samples
• Perform DNA extraction and purification from various sample types, including whole blood, plasma, and tissue
• Execute library preparation and DNA sequencing using platforms such as iSeq, MiSeq i100, NovaSeq6000, and NovaSeqX
• Maintain accurate tracking of samples using a Laboratory Information Management System (LIMS) and database queries
• Maintain laboratory instruments in good operating condition, perform routine preventive maintenance, and troubleshoot equipment malfunctions using the ticketing system
• Perform consumables, reagents, and samples inventory as needed
• Draft and refine Standard Operating Procedures (SOPs) through an iterative process guided by senior scientists
• Maintain precise, well-organized laboratory records, worksheets, and notebooks
• Adhere to environmental, health, and safety (EHS) guidelines, as well as Good Laboratory Practices (GLP)
• Treat quality as foundational by delivering accurate, reproducible, and clean data
• Take ownership of the work, executing tasks and adapting to evolving project needs without waiting for a finished playbook
• Handle protected health information (PHI) in paper and electronic formats as required to perform duties

QUALIFICATIONS:

• Minimum of a BS/BA in a biological science or equivalent
• 1 to 4 years of hands-on Molecular Biology laboratory experience

KNOWLEDGE, SKILLS, AND ABILITIES:

• Must have proven, hands-on experience utilizing molecular biology techniques, including pipetting, PCR/qPCR, and nucleic acid extraction
• Experience with PCR library preparation for Next-Generation Sequencing (NGS) and running sequencing platforms
• Practical knowledge of LIMS and proficiency in sample tracking
• Demonstrated experience handling delicate biological materials and following rigorous research protocols
• Excellent oral and written communication skills to actively share precise data and help the broader team troubleshoot
• Proficiency in Microsoft Excel is required; advanced Excel skills (e.g., nested formulas, macros, pivot tables) and database querying capabilities are highly desired
• Experience with sample analysis and QC, including electrophoresis and DNA quantification techniques
• Ability to investigate and create new methods or technologies to advance project timelines
• Strong troubleshooting skills with the ability to recognize subtle malfunctions and resolve issues

ADDITIONAL JOB DESCRIPTION:

• This role requires onsite work in San Carlos and flexibility to work shifted schedules (e.g., 7am - 4pm, 11am - 8pm, 7pm - 3am) with a 30-minute break.